A PDO thread lift can be used to tighten and smooth the skin on the face. Reduce the appearance of wrinkles, including nasolabial folds. Smooth PDO threads are commonly placed in a cross-hatched pattern of 5 threads perpendicular to 5 other threads to cover a small area of the face on each side. So, typically you would need 10 per side or more for a procedure to treat an area.