Bellafill is a cosmetic dermal filler. It's used to improve the appearance of wrinkles and correct facial contours for a more youthful appearance. It's an injectable filler with a collagen base and polymethyl methacrylate (PMMA) microspheres. It is a long-lasting dermal filler approved by the FDA to treat wrinkles and skin folds. It’s also the only filler approved to treat acne scarring. Juvederm is a temporary hyaluronic acid-based dermal filler approved by the FDA to temporarily treat wrinkles and skin folds on the face.